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Table 1 Hepatitis C micro-elimination progress in target populations in the Netherlands in 2017

From: Strategies for achieving viral hepatitis C micro-elimination in the Netherlands

 

Population size (N)

HCV seroprevalence (%)

Total chronic HCV infections (HCV RNA (+)) (N)

HCV infections cured (N)/(%)

Source/Comments

Main actions/interventions to facilitate HCV elimination

HIV-infected

22,900

12%

1471 (R)

1124/76%

[24, 27]

• Behavioral counseling.

• Once in a lifetime or frequentc screening (depending on risk behavior).

Hemophilia patients (born < 1992)

NA

NA

700 (R)

190/27.1%

[25] (Combined Dutch & UK cohort)

• Once in a lifetime screening.

• Treatment scale-up.

High-risk MSM (HIV-negative)b

NA

4,8%

NA

NA/NA

[57]

• Behavioral counseling.

• Frequentc screening

• Early treatment in case of (re) infection.

Migrants from high endemic countries

1,527,032

NA

13,819 (E)

NA/NA

[58]

• Raise awareness of HCV through local/multimedia information campaigns.

• Once in a lifetime screening for first-generation migrants with HCV prevalence ≥2% in country of origin.

PWID

14,000

39–74%

4040–7666 (C)

NA/NA

[7, 12,13,14,15,16, 59]

• Once in a lifetime or frequentc screening (depending on risk behavior).

• Treatment scale up.

Prisoners

10,194/each day

7.4–13.9%

558–1049 (C)

NA/NA

[60,61,62]

• Educate prison doctors on HCV.

• Once in a lifetime or frequentc screening (depending on risk behavior).

• Include detainees in regular health insurance.

Hemodialysis patients

17,132

NA

NA

NA/NA

[63]

• Once in a lifetime screening.

Health care workersd

NA

NA

NA

NA/NA

–

• Once in a lifetime screening by employer.

General Dutch population

17,081,507a

0.1–0.4%

12,640–50,561 (C)

4427/8–35%

[7, 29]

• Raise awareness of HCV through multimedia information campaigns.

• Educate general practitioners on HCV to increase compliance with viral hepatitis screening and referral guidelines.

• Trace and treat HCV infected lost to follow-up.

  1. PWID people who (have ever) inject(ed) drugs, MSM men who have sex with men, NA not available. (R) = reported numbers from publications of registries; (E) = estimated numbers reported in studies; (C) = calculated from seroprevalence estimates multiplied by .74 (assumed spontaneous clearance rate of 26%)
  2. a https://opendata.cbs.nl/statline/#/CBS/nl, Dutch population numbers in 2017
  3. b MSM with high-risk sexual activities
  4. c One to four times per year
  5. d Health care workers who perform hazardous tasks, putting them at risk for acquiring of transferring a hepatitis C infection (definition from the National Health Council) [4]